| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9308076 | Journal of Renal Nutrition | 2005 | 6 Pages |
Abstract
This article reviews bone adaptation to microgravity, during manned space missions, in humans undergoing Head Down Tilt (HDT) and in Hind-Limb-Suspended Rats. Under microgravity conditions, bone loss occurs in association with hypercalciuria, which in turn modulates Aquaporin 2 (AQP2) excretion in urine, thus avoiding stone forming in space. This report discloses the need to prevent bone loss in order to prepare for long stays at lunar bases or voyages to Mars.
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Authors
Natale MD, Massimo MD, Giovanna PhD, Alessandra MD, PhD, Pietro MD, Christian MD, PhD,