Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9308278 | Kidney International | 2005 | 10 Pages |
Abstract
Iron sucrose and iron gluconate (but not iron dextran) can induce MCP-1 generation in renal and extrarenal tissues, possibly via transcriptional events. This may dramatically impact renal disease-induced MCP-1 increments. Finally, iron can increase peritoneal lavage fluid MCP-1 levels. Whether the above changes have implications for renal disease progression, and/or for peritoneal inflammation/peritoneal dialysis efficiency, are issues which may need to be addressed.
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Authors
Richard A. Zager,