Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9308287 | Kidney International | 2005 | 12 Pages |
Abstract
Podocyte apoptosis induced by TGF-β1 and puromycin aminonucleoside requires p21, and Bcl-2 plays a crucial role downstream of p21 in mediating this effect. These results suggest that p21 may play a critical role in the decrease in podocyte number in disease status accompanied by increased TGF-β1.
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Authors
Takehiko Wada, Jeffrey W. Pippin, Yoshio Terada, Stuart J. Shankland,