Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9308405 | Kidney International | 2005 | 8 Pages |
Abstract
The results indicate a strong nephroprotective effect of the vasopeptidase inhibitor in this animal model of progressive renal fibrosis. Besides the antihypertensive action of AVE7688, its antifibrotic, anti-inflammatory, and antiproteinuric effects demonstrated in the present study may serve as an important therapeutic option for chronic inflammatory and fibrotic diseases in man.
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Authors
Oliver Gross, Marie-Louise Koepke, Bogdan Beirowski, Eckhard Schulze-Lohoff, Stephan Segerer, Manfred Weber,