Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9308432 | Kidney International | 2005 | 9 Pages |
Abstract
Nonselective NOS inhibition increases the oxygen costs of kidney function independent of Ang II. Kidney NOS-1 is responsible for these in vivo and in vitro effects. In vitro observations suggest that NOS-1 acts in part via effects on basal metabolism and mitochondrial function.
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Authors
Aihua Deng, Cynthia M. Miracle, Jorge M. Suarez, Mark Lortie, Joseph Satriano, Scott C. Thomson, Karen A. Munger, Roland C. Blantz,