| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9308466 | Kidney International | 2005 | 14 Pages |
Abstract
Relaxin is a potent inhibitor of TGF-β1-induced extracellular matrix (ECM) synthesis and secretion as well as fibroblast activation. Furthermore, it induces ECM degradation by induction of MMP-2 and MMP-9. These effects are mediated, at least in part, by inhibition of TGF-β1 signaling.
Keywords
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Authors
Malte H.J. Heeg, Michael J. Koziolek, Radovan Vasko, Liliana Schaefer, Kumar Sharma, Gerhard A. Müller, Frank Strutz,