Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9308557 | Kidney International | 2005 | 8 Pages |
Abstract
In childhood SSNS, there is a qualitative and quantitative difference in urinary heparanase activity expression that is not paralleled in adult nephrotic syndrom. These data suggest that dysregulated heparanase expression may play a significant role in the pathogenesis of SSNS, possibly through an abnormality in post-translational control of latent heparanase activation.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Nephrology
Authors
Richard C.L. Holt, Nicholas J.A. Webb, Shirley Ralph, John Davies, Colin D. Short, Paul E.C. Brenchley,