Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9308561 | Kidney International | 2005 | 10 Pages |
Abstract
Mechanical stretch induces hypertrophy in podocytes in vitro in all phases of the cell cycle. This effect is cell cycle dependent, and requires p21, Erk1/2, and Akt. Stretch may play a role in podocyte injury when intraglomerular pressure is increased. See Editorial by Kriz and Endlich, p. 373.
Related Topics
Health Sciences
Medicine and Dentistry
Nephrology
Authors
Arndt T. Petermann, Jeffrey Pippin, Raghu Durvasula, Raimund Pichler, Keiju Hiromura, Toshi Monkawa, William G. Couser, Stuart J. M.D.,