Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9308565 | Kidney International | 2005 | 8 Pages |
Abstract
Our findings indicate the possibility that TGF-β1 transcriptionally inhibits prostasin expression by the induction of IκBα and the subsequent inhibition of NF-κB/Rel activity in M-1 cells, and also suggest the possibility that TGF-β1 might inhibit sodium reabsorption through a reduction in prostasin expression and subsequent inhibition of ENaC activity.
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Authors
D.O. G.I.A. Tuyen, Kenichiro Kitamura, Masataka Adachi, Taku Miyoshi, Naoki Wakida, Junko Nagano, Hiroshi Nonoguchi, Kimio M.D., Ph.D.,