Clinical cross-over comparison of mid-dilution hemodiafiltration using a novel dialyzer concept and post-dilution hemodiafiltration

On-line mid-dilution HDF with the Nephros OLpūr™ MD 190 hemodiafilter appears to be a true technologic step ahead in terms of improved middle molecule removal. This efficient procedure gives hope to play a role in preventing or at least retarding dialysis-related long-term complications, such as β2m amyloidosis, in ESRD patients, and may contribute to a more adequate dialysis therapy.