Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9308993 | Kidney International | 2005 | 13 Pages |
Abstract
Promotion of tubular epithelial proliferation and survival, and interstitial cell apoptosis, may minimize renal fibrosis after UUO. In the present study, both were linked spatially and temporally with increased pERK expression. Fluvastatin treatment attenuated UUO-induced fibrosis via an antioxidant and pERK-related mechanism.
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Authors
Betty Pat, Tao Yang, Chuize Kong, Dianne Watters, David W. Johnson, Glenda Gobe,