Article ID Journal Published Year Pages File Type
9309093 Kidney International 2005 9 Pages PDF
Abstract
These in vitro studies indicate that (1) tubular epithelial cells chemoattract endothelial cells in a paracrine fashion by secreting VEGF, and (2) VEGF stimulates proliferation and promotes survival of renal epithelial cells in an autocrine manner via VEGFR-2. Taken together, our results suggest that VEGF supports the growth of renal epithelia in addition to mediating kidney vascularization.
Related Topics
Health Sciences Medicine and Dentistry Nephrology
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