Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9309093 | Kidney International | 2005 | 9 Pages |
Abstract
These in vitro studies indicate that (1) tubular epithelial cells chemoattract endothelial cells in a paracrine fashion by secreting VEGF, and (2) VEGF stimulates proliferation and promotes survival of renal epithelial cells in an autocrine manner via VEGFR-2. Taken together, our results suggest that VEGF supports the growth of renal epithelia in addition to mediating kidney vascularization.
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Authors
Guillermo Villegas, Bäerbel Lange-Sperandio, Alda Tufro,