| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9310728 | Kidney International | 2005 | 12 Pages |
Abstract
Modifier loci in the genetic background are important factors in inter- and intrafamilial variability in the phenotypic expression of PKD1. The extreme intrafamilial phenotype differences are consistent with the hypothesis that one or a few modifier genes have a major effect on the progression and severity of PKD1.
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Authors
Pamela R. Fain, Kimberly K. McFann, Matthew R.G. Taylor, Maryellyn Tison, Ann M. Johnson, Berenice Reed, Robert W. Schrier,