Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9310746 | Kidney International | 2005 | 13 Pages |
Abstract
These data show that Milan hypertensive rats are not susceptible to diabetic nephropathy, at variance with glomerulosclerosis-prone Milan normotensive rats, thus indicating the importance of genetic background. Our study suggests that the nature of this (genetic) protection might be hemodynamic, with intrarenal artery hypertrophy preventing diabetes-induced loss of autoregulation.
Keywords
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Nephrology
Authors
Giuseppe Pugliese, Flavia Pricci, Paola Barsotti, Carla Iacobini, Carlo Ricci, Giovanna Oddi, Giulio Romeo, Gaetano Leto, Giuseppe Marano, Mariella Sorcini, Massimo Sabbatini, Giorgio Fuiano, Umberto Di Mario, Francesco Pugliese,