Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9311920 | Urology | 2005 | 5 Pages |
Abstract
Intravesical BTX-A inhibits bladder sensory mechanisms by reducing the frequency of bladder contractions in an SCI rat model. Furthermore, our results suggest that intravesically applied BTX-A does not penetrate to the smooth muscle layer even after PS disruption of the bladder urothelium. These findings may have important clinical applications in treating overactive bladders after SCI.
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Authors
Mohit Khera, George T. Somogyi, Nilson A. Salas, Susanna Kiss, Timothy B. Boone, Christopher P. Smith,