Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9312243 | Urology | 2005 | 6 Pages |
Abstract
In tumors and adjacent normal uroepithelium of patients with TCC, three major cytosolic GST classes, Mu, Pi, and Theta, were expressed. Although the GST isoenzyme pattern in TCC was similar to that of the corresponding normal uroepithelium, during cancer progression a clear tendency toward an increase in all the GST subtypes expressed was noted. For the first time, distinct GSTT1-1 activity levels were demonstrated in human uroepithelium, as well as its pronounced upregulation in TCC.
Related Topics
Health Sciences
Medicine and Dentistry
Nephrology
Authors
T. Simic, J. Mimic-Oka, A. Savic-Radojevic, M. Opacic, M. Pljesa, D. Dragicevic, M. Djokic, R. Radosavljevic,