| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9319423 | European Urology | 2005 | 5 Pages |
Abstract
This is the first report providing experimental support for chronic dosing with sildenafil which could be of use for patients that are poor responders to on-demand treatment. Chronic sildenafil may regulate the transduction pathway leading to the activation of eNOS but has no effect on NO bioavailability or on the cGMP pathway, thereby eliminating a possible concern for tachyphylaxis.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Obstetrics, Gynecology and Women's Health
Authors
Delphine Behr-Roussel, Diane Gorny, Katell Mevel, Stéphanie Caisey, Jacques Bernabé, Gillian Burgess, Chris Wayman, Laurent Alexandre, François Giuliano,