Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9320367 | European Urology | 2005 | 9 Pages |
Abstract
Neo-adjuvant adenovirus-mediated cytotoxic gene therapy prior to prostatectomy for prostate cancer is feasible and safe in an outpatient setting for intraprostatic vector doses up to 2Â ÃÂ 1011 viral particles. Activation of the immune system was observed. Application of higher vector doses may be considered.
Keywords
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Authors
R.R.M. van der Linden, B.L. Haagmans, P. Mongiat-Artus, G.J. van Doornum, R. Kraaij, D. Kadmon, E. Aguilar-Cordova, A.D.M.E. Osterhaus, T.H. van der Kwast, C.H. Bangma,