| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9323557 | Fertility and Sterility | 2005 | 7 Pages |
Abstract
Heparanase was found to be constitutively expressed by blastocyst-stage embryos. Moreover, the amount of heparanase was markedly increased by incubation of morulae with recombinant heparanase, evaluated by immunostaining and enzymatic activity. Heparanase supplementation resulted in approximately a twofold increase in embryo implantation rate in vivo. Taken together, these data suggest that heparanase is actively involved in embryo implantation.
Related Topics
Health Sciences
Medicine and Dentistry
Obstetrics, Gynecology and Women's Health
Authors
Ariel M.D., Aharon B.Sc., Moriah M.Sc., Asher M.D., Orit Ph.D., Eyal Ph.D., Helena Ph.D., Israel Ph.D.,