Article ID Journal Published Year Pages File Type
9323679 Fertility and Sterility 2005 9 Pages PDF
Abstract
Immature sperm contain high nicotinamide adenine dinucleotide phosphate (NADPH) in cytoplasmic droplets, but it has not yet been clear whether abnormal sperm morphology plays any role in sperm DNA damage induced by oxidative stress. Our data support the role of NAPDH in ROS-mediated sperm DNA damage and suggest that abnormal sperm morphology combined with elevated ROS production may serve as a useful indicator of potential damage to sperm DNA.
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Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
Preview
Impact of sperm morphology on DNA damage caused by oxidative stress induced by β-nicotinamide adenine dinucleotide phosphate
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