Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9323724 | Fertility and Sterility | 2005 | 7 Pages |
Abstract
Nicotine appears to activate specific intracellular death-related pathways, probably by bax-dependent activation of caspase-3, inducing apoptosis in Leydig cells. Thus, nicotine-induced apoptosis of Leydig cells might be one of the important mechanisms behind nicotine-related urogenital disorders in men.
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Authors
Khae-Hawn M.D., M.Sc., Kwan-Joong M.D., Heung-Jae M.D., Ph.D., Chil-Hun M.D., Ph.D., Mi-Hyeon Ph.D., Chang-Ju M.D., Ph.D.,