Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9325022 | Fertility and Sterility | 2005 | 7 Pages |
Abstract
Chromosome self-normalization occurs in a significant proportion of chromosomally abnormal embryos, possibly because of the loss of a chromosome in trisomic cells after blastocyst stage. Thus chromosomally abnormal embryos are a potential source of disomic stem cells. Not all chromosomally abnormal embryos self-corrected. Abnormal stem cells that might be derived could be used as models to study the effect of chromosomal abnormalities on human development.
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Authors
Santiago Ph.D., Esther M.Sc., Pere Ph.D., Mercedez Garcia Ph.D., Mohan C. Ph.D., Nury Ph.D., John Ph.D., Jacques Ph.D.,