| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9325035 | Fertility and Sterility | 2005 | 7 Pages |
Abstract
The study has shown DNA fragmentation in human oocytes unfertilized after ICSI. The evidence is confirmed as well in control oocytes, free from in vitro culture or manipulation stress. Caspase-3 immunoassay suggests the presence of apoptosis. The high percentage of oocytes demonstrating DNA fragmentation in the unfertilized oocytes could be correlated with fertilization failure.
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Authors
Liana Ph.D., Giovanni Sc.D., Giovanni Morici, Maurizio Sc.D., Ettore M.D., Maria C. Sc.D.,