Article ID Journal Published Year Pages File Type
9325235 Fertility and Sterility 2005 10 Pages PDF
Abstract
Mifepristone inhibited cell growth by arresting cell cycle progression at S phase, induced apoptosis through caspase-3 activation, and modulated apoptosis regulatory genes BCL2/BAX and FAS/FASLG in Ishikawa cells. Together, these data imply that the improvement in breakthrough bleeding observed with mifepristone might be due to diminished volume of endometrial tissue similar to that seen with endometrial atrophy.
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Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
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Effect of mifepristone on proliferation and apoptosis of Ishikawa endometrial adenocarcinoma cells
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