Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9327397 | Gynecologic Oncology | 2005 | 9 Pages |
Abstract
The loss of Fas and the deregulation of FasL, DR4, DR5, and TRAIL in the CIN-cervical cancer sequence suggest a possible functional role of these death ligands and receptors during cervical carcinogenesis. The frequent expression of DR4 and DR5 presents these receptors as promising targets for innovative therapy modalities in cervical cancer.
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Authors
N. Reesink-Peters, B.M.T. Hougardy, F.A.J. van den Heuvel, K.A. ten Hoor, H. Hollema, H.M. Boezen, E.G.E. de Vries, S. de Jong, A.G.J. van der Zee,