| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9327628 | Gynecologic Oncology | 2005 | 9 Pages |
Abstract
These results collectively indicate that the development of resistance in OVCAR-3 cells was derived by increased PIK3CA transcription and reduction of PTEN expression. These alterations conferred cisplatin resistance to cisplatin through the activation of PI3K/Akt and the inhibition of Bax translocation.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Obstetrics, Gynecology and Women's Health
Authors
Sooyong Lee, Eui-Ju Choi, Changbae Jin, Dong-Hyun Kim,