Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9327628 | Gynecologic Oncology | 2005 | 9 Pages |
Abstract
These results collectively indicate that the development of resistance in OVCAR-3 cells was derived by increased PIK3CA transcription and reduction of PTEN expression. These alterations conferred cisplatin resistance to cisplatin through the activation of PI3K/Akt and the inhibition of Bax translocation.
Keywords
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Authors
Sooyong Lee, Eui-Ju Choi, Changbae Jin, Dong-Hyun Kim,