L'apoptose : bases fondamentales et applications médicales

Apoptosis has become a most popular concept of cell death. What makes apoptosis particularly exciting for medicine is that its dysfunctions play a central role in the pathogenesis of several human diseases. This review summarizes the considerable knowledge about the cell death pathways. The purpose of this article is to provide a background of relevance to clinicians on apoptosis, and the rationale for future therapeutic interventions directed toward the apoptotic machinery.