Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9335380 | Reproductive BioMedicine Online | 2005 | 4 Pages |
Abstract
The aim of this study was to determine if blastocyst frozen embryo transfers are able to reduce the potential for the rate of high order multiples (HOM) (>2 fetal sacs) without affecting the overall pregnancy and implantation potential. Group A included all frozen blastocyst transfers prior to 1 January 2002. Group B included all frozen blastocyst transfers between 1 January 2002 and 12 December 2003. There was no significant difference for survival for the two time periods (79 versus 80%). A significantly (P < 0.05) lower number of embryos were transferred in group B (1.9) compared with group A (2.8). There was a significant (P < 0.05) reduction of (HOM) from 31 to 3% for groups A and B respectively. Ongoing pregnancy rates for group A resulted in 52% of 25 embryo transfers and 41% of 75 embryo transfers in group B (not significant). Reducing the number of embryos transferred between groups A and B did not significantly impact implantation rates. It is concluded that blastocyst freezing is effective for overall survival, pregnancy and implantation while reducing the rate of high order multiples.
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Authors
Anthony R Anderson, Shan S Wilkinson, Sandy Price, Jack L Crain,