Improving patient-specific dosimetry for intravascular brachytherapy

Significant dose perturbations due to the presence of source curvature, metallic stents, calcified plaques, and guidewires have been found in IVBT for in-stent restenosis. Because it has been reported that, with the current prescriptions for IVBT, higher doses consistently improve treatment outcomes, the empirical method derived from this work can be used to assess cold spots dosimetrically, thus improving patient-specific dosimetry for IVBT.