Primary meningioma of the mandible

We reported a case of primary extracranial meningioma in the mandible of a 10 year-old-boy with basal cell nevus syndrome. The tumor had a well-delineated large round shaped radiolucency including an impacted canine in the mandible. Microscopic examination revealed a fibrous tumor composed of uniform spindle-shaped cells and fine collagen bundles. The spindle-shaped cells were arranged in whorls and interconnecting fascicles, and some nuclear pseudoinclusion and psammoma bodies were detected. Immunohistochemically, the tumor cells were stained for epithelial membrane antigen, vimentin and desmoplakin, but not for S-100 protein. No recurrence of the tumor was detected for 4 years.