| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9346366 | Ophthalmology | 2005 | 4 Pages |
Abstract
Given our recent finding of elevated iron levels in the RPE of patients with age-related macular degeneration (AMD), it is interesting that retinal iron overload in aceruloplasminemia is associated with a maculopathy that clinically resembles AMD. This finding supports the hypothesis that retinal iron homeostasis is essential for normal retinal function. Disruption of iron homeostasis could contribute to the pathogenesis of AMD.
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Authors
Joshua L. MD, PhD, Chimene BA, Edward P. MD, Robert L. MD, Tomas S. MD, John F. MD, PhD, Earl A. MD, David G. MD, PhD,