Article ID Journal Published Year Pages File Type
9353963 Journal of Orthopaedic Research 2005 9 Pages PDF
Abstract
Conclusion: Our results indicate that fibroblasts in periprosthetic tissues are capable of inducing the differentiation of normal human peripheral blood mononuclear cells to mature osteoclasts by a mechanism that involves both RANKL and TNFα. Suppression of both RANKL and inflammatory cytokines is likely to be required to control periprosthetic osteolysis.
Related Topics
Health Sciences Medicine and Dentistry Orthopedics, Sports Medicine and Rehabilitation
Authors
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