Serous cystic neoplasms of the pancreas

Pancreatic serous neoplasms are rare but account for the most common type of pancreatic cystic neoplasms. The vast majority of serous cystic tumours are benign (serous cystadenoma). A few cases of clinically more aggressive and metastatic serous tumours have been reported in the literature, and designated as malignant (serous cystadenocarcinoma). Due to the rarity of malignant pancreatic serous neoplasms, their true incidence is still unclear. Serous cystic neoplasms of the pancreas can be a diagnostic challenge, since they exhibit overlapping clinical, radiological and even histological features with other pancreatic cystic lesions, namely mucinous cystic tumours and pseudocysts. Complete surgical resection is curative.