Mucinous cystic neoplasms of the pancreas

Mucinous cystic neoplasms (MCNs) of the pancreas are rare neoplasms characterized by predominance in women, lack of communication with the pancreatic duct system, and the presence of distinctive ovarian-like stroma. They comprise a spectrum of neoplasia ranging from mucinous cystadenomas to borderline MCNs to invasive mucinous cystadenocarcinomas. Many investigators have found that histologically benign MCNs may become malignant if not completely excised, supporting a progression model for MCNs. Adequate sampling of the specimen is essential to obtain an accurate diagnosis since only small portions of the tumour may contain areas of malignancy. As a result, some have recommended that the entire specimen should be examined. Complete excision is the treatment of choice for all MCNs of the pancreas.