Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9366945 | Pathologie Biologie | 2005 | 9 Pages |
Abstract
Two different anti-ageing cosmetic actives based respectively, on dermal compartment regeneration and on dermoepidermal reinforcement, have been developed using tissular engineering models. Conjointly use of different innovative three-dimensional models such as reconstructed dermis and skin built with human cells coming from variable aged donors allowed first, a better understanding of matrix modifications due to ageing and second, the screening of active ingredients highly targeted to reverse observed damages. The validity of such three-dimensional models has been then confirmed by in vivo studies on healthy volunteers.
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Authors
V. André, S. Grenier, F. Pivard, E. Perrier,