Article ID Journal Published Year Pages File Type
9373455 Journal of Pediatric Surgery 2005 5 Pages PDF
Abstract
Neuroblastoma initially upregulates CCR7 expression by DC. However, with tumor progression, this chemokine is downregulated, likely leading to impaired DC migration. Immunotherapeutic strategies to bypass or augment CCR7-dependent DC trafficking may improve survival for patients with aggressive disease.
Related Topics
Health Sciences Medicine and Dentistry Perinatology, Pediatrics and Child Health
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