| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9377513 | Biological Psychiatry | 2005 | 7 Pages |
Abstract
Experimental HD was also associated with enhanced frequency of sIPSCs, a result consistent with the conclusion that loss of cannabinoid-mediated control of GABA transmission might contribute to hyperactivity of GABA synapses in the striatum of HD mice. Accordingly, spontaneous excitatory postsynaptic currents, which were not upregulated in R6/2 mice, were still sensitive to cannabinoid receptor stimulation.
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Authors
Diego Centonze, Silvia Rossi, Chiara Prosperetti, Anne Tscherter, Giorgio Bernardi, Mauro Maccarrone, Paolo Calabresi,