Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9377532 | Biological Psychiatry | 2005 | 7 Pages |
Abstract
The increased striatal activation on trials that violated the sequence demonstrates a greater response to negative feedback for depressed compared with control subjects. Our observations of significant differences in both prefrontal and striatal regions in the depressed elderly subjects relative to elderly control subjects supports the frontostriatal dysfunction hypothesis of late-life depression.
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Biological Psychiatry
Authors
Howard J. Aizenstein, Meryl A. Butters, Jennifer L. Figurski, V. Andrew Stenger, Charles F. III, Cameron S. Carter,