| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9377714 | Biological Psychiatry | 2005 | 6 Pages |
Abstract
Clozapine treatment resulted in a global reduction in [123I]CNS-1261 binding to the NMDA receptor intrachannel PCP/MK-801 site in vivo. This supports an effect of the drug on glutamatergic systems that could be exploited for future antipsychotic drug discovery.
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![Impact of Schizophrenia and Chronic Antipsychotic Treatment on [123I]CNS-1261 Binding to N-Methyl-D-Aspartate Receptors In Vivo](/preview/png/9377714.png "First Page Preview: Impact of Schizophrenia and Chronic Antipsychotic Treatment on [123I]CNS-1261 Binding to N-Methyl-D-Aspartate Receptors In Vivo")
Authors
Rodrigo A. Bressan, Kjell Erlandsson, James M. Stone, Rachel S. Mulligan, John H. Krystal, Peter J. Ell, Lyn S. Pilowsky,