Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
937837 | Neuroscience & Biobehavioral Reviews | 2013 | 14 Pages |
Abstract
⺠Neurosteroids potently modulate GABAA receptors. ⺠GABA is involved in biology of stress and depression. ⺠Neurosteroids are involved in the biology of stress and depression.
Keywords
NMDARsIPSCsTranslocator protein 18 kDaSSRIsCYP11A15α-DHPlogPGABAARsBDZTSPODHEASVDACANTACTHrTMS3α-HSDalloPDBIECTCRH3α-hydroxysteroid dehydrogenase5α-dihydroprogesteroneneurosteroidsPREGSStressNeuroactive steroidsγ-aminobutyric acidAnxietyDepressionallopregnanolonebenzodiazepineRepetitive transcranial magnetic stimulationfunctional magnetic resonance imagingfMRIlong-term potentiationLTPinhibitory postsynaptic currentsadenine nucleotide transporterElectroconvulsive therapyCNSStardehydroepiandrosterone sulfatepregnenolone sulfatecentral nervous systemPVNCerebrospinal fluidCSFdiazepam binding inhibitorselective serotonin reuptake inhibitorsHPAparaventricular nucleusadrenocorticotrophic hormonecorticotrophin releasing hormonehypothalamic-pituitary-adrenalHippocampusSteroidogenic acute regulatory proteinvoltage-dependent anion channelGABAGABAA receptors
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Authors
Charles F. Zorumski, Steven M. Paul, Yukitoshi Izumi, Douglas F. Covey, Steven Mennerick,