| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9380638 | Journal of Affective Disorders | 2005 | 7 Pages |
Abstract
This study did not find abnormally reduced levels of NAA in left DLPFC of adult bipolar patients, in a sample of patients who were mostly on medications. However, elevated NAA/PCr+Cr ratios were shown in lithium-treated bipolar patients. Longitudinal 1H MRS studies should further examine NAA levels in prefrontal cortex regions in untreated bipolar patients before and after mood stabilizing treatment.
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Authors
Paolo Brambilla, Jeffrey A. Stanley, Mark A. Nicoletti, Roberto B. Sassi, Alan G. Mallinger, Ellen Frank, David Kupfer, Matcheri S. Keshavan, Jair C. Soares,