Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9385952 | Respiratory Medicine | 2005 | 4 Pages |
Abstract
Rheumatoid arthritis (RA)-associated constrictive bronchiolitis is a severe condition with no established efficient treatment. A 55-year-old woman with seropositive RA developed rapidly progressive constrictive bronchiolitis confirmed by lung biopsy. Her clinical condition worsened despite steroids and azathioprine. Treatment with etanercept-a tumor necrosis factor (TNF)-α inhibitor-combined with methotrexate, resulted in a marked improvement of both her clinical condition and pulmonary function tests. Treatment with TNF-α inhibitors and methotrexate may be proposed in RA-associated constrictive bronchiolitis, a severe condition hitherto not amenable to improvement.
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Authors
Alexis Benjamin Cortot, Vincent Cottin, Pierre Miossec, Eric Fauchon, Françoise Thivolet-Béjui, Jean-François Cordier,