| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9391347 | Journal of Vascular and Interventional Radiology | 2005 | 9 Pages |
Abstract
Alfimeprase in doses as high as 0.5 mg/kg was generally well-tolerated in patients with chronic PAO. No bleeding complications were noted. The stable fibrinogen concentrations suggest that the activity of alfimeprase may be limited to the target thrombus. Alfimeprase holds the potential to achieve dissolution of thrombus with a diminished risk of hemorrhage.
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Authors
Kenneth MD, Jacob MD, Fred A. MD, Herbert MD, Donald MD, John MD, Laura Gruneiro, Christopher F. Toombs, Fong Wang-Clow, Margie Mohler, Luis Pena, Ching-Yi Wan, Steven R. MD,