| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9402296 | Journal of Surgical Research | 2005 | 6 Pages |
Abstract
Incremental changes in plasma ANG II induce de novo production of ANG II in the non-ischemic kidney to augment intrarenal ANG II content. ACE inhibition blocks this positive feedback loop, suggesting that ANG II activates the intrarenal RAS by an ACE-dependent mechanism. The impact of ACE inhibition on blood pressure suggests that this feedback loop may be an important mechanism for maintenance of hypertension in RVH.
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Authors
Javid M.D., Gerald L. B.A., Chun-hua M.D., M. Burress M.D., J. Gregory M.D.,