Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9402369 | Journal of Surgical Research | 2005 | 7 Pages |
Abstract
The external esophageal perfusion model enabled precise control of the injurious agent. It induced the typical histological injury and cellular changes seen in severe reflux esophagitis. The cellular changes in apoptosis, proliferation and anti-oxidant defense make this model unique for reflux esophagitis studies. Further studies are needed to induce Barrett's esophagus and esophageal adenocarcinoma.
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Authors
Yan M.D., Ph.D., John M. M.D., Ruifeng R. B.S., Mukunda B. M.D., Ph.D., Whitney M.D., Robert C.G. M.D.,