Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9402433 | Journal of Surgical Research | 2005 | 7 Pages |
Abstract
We have shown that LPS and TNFα are potent mediators of STAT3 and SOCS3 expression in the pancreas and that the cytokines IL-6 and IL-1β are indirectly involved in the signaling pathway. Alteration of the STAT pathway should be explored as a therapeutic target for treatment of pancreatic inflammation.
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Authors
Linda C. Ph.D., Krista A. Ph.D., Usman M.D., Erik B.S., David W. (F.A.C.S.),