| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9402436 | Journal of Surgical Research | 2005 | 7 Pages |
Abstract
Plasmin induces smooth muscle cell proliferation. Plasmin induced ERK1/2 phosphorylation occurs through two pathways: one which is Gαi mediated/PI3-K dependent and a second which is Gαq mediated/PI3K independent. p38MAPK appears not to be involved in plasmin-mediated cell proliferation. This pattern of activation is distinct from that seen with urokinase plasminogen activator.
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Authors
Suzanne M. Ph.D., Elisa B.S., Irfan I. M.D., Mark G. M.D., Ph.D.,