Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9402449 | Journal of Surgical Research | 2005 | 6 Pages |
Abstract
Signaling through the ERK/MAPK pathway is required for efficient αvβ3-mediated migration on FBG. Inhibition of αvβ3-mediated migration by the integrin α5β1 correlates with altered intensity and duration of ERK/MAPK activation, but not FAK activation, in response to adhesion. This suggests a mechanism for the regulatory effect of α5β1 on αvβ3-mediated cell migration.
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Authors
Daphne P. Ly, Siobhan A. Corbett,