| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9402477 | Journal of Surgical Research | 2005 | 5 Pages |
Abstract
Chymase activity is up-regulated in the ischemic kidney of 2K1C rats. Plasma ANG II does not appear to regulate intrarenal chymase activity, suggesting that ischemia per se up-regulates chymase activity in the kidney. ACE-independent ANG II production by chymase may provide a mechanism for augmenting intrarenal ANG II in the ischemic kidney in RVH.
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Authors
Javid M.D., Gerald L. B.A., Chun-hua M.D., M. M.D., Mark C. Ph.D., J. M.D.,