Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9402688 | Journal of Surgical Research | 2005 | 9 Pages |
Abstract
Our results suggest that: (1) local injection of sub-bactericidal doses of protamine sulfate reduces the virulence of P. aeruginosa; (2) this effect is due to interference with the systemic rather than local spread of P. aeruginosa; and (3) local application of protamine sulfate may have potential as supportive therapy for prevention of systemic P. aeruginosa infection in severely burned patients.
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Authors
Allan M.D., Kendra P. Ph.D., Pyong Woo Ph.D., Abdul N. Ph.D., John A. M.D.,